The causes behind residual hearing loss following cochlear implantation are complex and varied. Studies such as this one provide clues as to what to focus on in order to improve the acoustic experience of cochlear implant recipients.
Genetic Reprogramming Converts Nonsensory Cells into Sensory Cells in the Mature Cochlea
We have artificially expressed three key hair cell fate promoting proteins in nonsensory cells of adult mice, and found that a significant number of these cells will convert into cells resembling hair cells. This offers a potential strategy for hair cell regeneration.
Changes in the Brain with Age and Hearing Loss
A better understanding of how our brains process patterns with aging and hearing loss, and when neural responses are exaggerated versus diminished, can aid in developing treatments and devices to improve age- and hearing loss-related hearing difficulties.
Meet the 2024 Emerging Research Grants Scientists
As of this year, our general hearing health grants have been renamed Elizabeth M. Keithley, Ph.D. Early Stage Investigator Awards in recognition of Keithley’s impact on the field and long service to HHF, and the awards’ focus on supporting the next generation.
Potential Therapy for Blast-Induced Hearing Loss and Tinnitus
These findings suggest that by inhibiting PARP1, a protein, it may be possible to maintain the health and survival of hair cells following blast injuries. The restoration of energy production from both mitochondria and glycolysis contributes to this protective effect.
Scientists Discover Repair Process That Fixes Damaged Hair Cells
The hair cells deploy a protein called XIRP2, which can sense damage to the cores that are made of a substance called actin. The researchers found that XIRP2 first senses damage, then migrates to the damage site and repairs the cores by filling in new actin.
HHF Is 65 This Year!
More funding and more time leads to more ambitious experimental plans, additional data collected, and a stronger footing for subsequent research and research funding.
ARO MidWinter Meeting in Person Again
The annual ARO MidWinter Meeting is the preeminent conference for scientists and clinicians conducting research in the hearing and balance fields. The 46th meeting just concluded after five days in Orlando, Florida—the first in-person conference since late January 2020.
Cell-Type Identity of the Chick Balance Organ
We have now identified the first events that lead to proliferative hair cell regeneration in birds, which provides new leads that can be translated to mice and ultimately to humans.