10 Fun Easter Facts From Our Mascot, the Baby Chick

By Tara Guastella

As you’ve seen on our previous blog posts, a baby chicken may hold the key to a cure for hearing loss and tinnitus. Chickens have the remarkable ability to restore their own hearing naturally by regrowing inner ear hair cells that, once they are damaged, lead to hearing loss.

In fact, most animals other than mammals can regenerate these delicate cells, regaining their hearing after the cells are damaged by noise, age, or ototoxic drugs. This is the basis for the work of our Hearing Restoration Project, which is aiming to translate this remarkable capacity to humans.

So with Easter right around the corner we thought our mascot, the baby chick, would provide you with 10 fun Easter facts:

1) Easter is the celebration of the resurrection of Christ three days after his death. It is the oldest Christian holiday and the most important day of the church year.

2) Like rabbits and hares, eggs and chicks are often associated with Easter because, in pagan times, they were signs of fertility and new life.

3) After Halloween, Easter is the biggest candy-consuming holiday. About 120 million pounds of candy are bought each year, enough to fill four dump trucks.

4) Roughly 90 million chocolate bunnies, 91.4 billion eggs, and 700 million Peeps (sugar-coated marshmallow sweets) are produced each year in the United States.

5) About 76 percent of people eat the ears on chocolate bunnies first.

6) Half of the states in the United States have banned the practice of dyeing live chicks for Easter.

7) To help Americans in need, egg farmers across the country are donating more than 11 million eggs to food banks across the nation.

8) The White House hosts an Easter Egg Roll on its Front Lawn each year. This tradition was started by President Rutherford B. Hayes in 1878.

9) Like many holidays, Easter also has its own catchy tunes or carols such as “Here Comes Peter Cottontail” and “Easter Parade.”

10) Some 16 billion jelly beans are made specifically for Easter, which is enough to fill a plastic egg the size of a nine-story building.

If you celebrate Easter this coming Sunday and enjoy chick-shaped marshmallows or other fun Easter candy, remember that it is a little chick that is helping us to achieve the next great medical breakthrough: curing hearing loss and tinnitus.

Is A Cure for Hearing Loss Possible?

By Shanna Groves

When Hearing Health Foundation approached Lipreading Mom about doing a story about curing hearing loss, I admit I was skeptical. Is a cure really possible? And if it is, would it benefit those who have embraced their deafness? I have many friends who haven’t been able to hear all their lives, and they lead very full lives. So why the need to change that?

Lipreading Mom recently conducted an email interview with Shari Eberts, Chairman of the Hearing Health Foundation’s (HHF) Board of Directors, about HHF’s research into hearing loss.

When did research into a hearing loss ‘cure’ first get support from the Hearing Health Foundation?

HHF’s founder, Collette Ramsey Baker, was steadfast in her support of funding for new technologies and treatments for hearing loss, despite objections and doubts from supporters and those in the industry. Because of that commitment, HHF has been a leader in driving new innovations and treatments for people with hearing loss for more than fifty years. This includes funding research that led to the development of cochlear implants and many of today’s standard treatments for otosclerosis (abnormal bone growth in the ear) and ear infections. Today, HHF continues to support groundbreaking research in hearing, through the search for a biological cure for hearing loss and tinnitus through its Hearing Restoration Project (HRP).

HRP officially launched in 2011 and is currently funding five projects from its consortium scientists, but the initial discovery that led to the HRP came many years before. Many types of hearing loss result from damage to the delicate hair cells of the inner ear. Humans can’t regrow these cells—but in a game-changing breakthrough in 1987, HHF-funded scientists discovered that birds can.

While studying how drugs that are known to cause hearing damage affect the tiny sensory cells in the ear, these scientists needed to permanently damage a chicken’s hair cells. For 10 days, research assistants administered a common antibiotic, known to cause hearing loss, to laboratory chickens. On day 11 many of the hair cells were lost and a few days later, even more were lost. Surprisingly, when the scientists looked three weeks later, almost all the hair cells had returned. They didn’t believe these results so they did the experiment again and again. Sure enough, chickens can naturally regenerate their inner ear hair cells, restoring their hearing after damage.

Our HRP Consortium is the dream team of hair cell regeneration, comprising the best auditory scientists at leading institutions worldwide such as Harvard and Stanford. With more than 200 years of combined experience in hearing research, the HRP Consortium publishes widely (over 400 published papers among them) and have well established labs (receiving over 600 NIH grants combined). We have every confidence we have the right team in place, and the right model to accelerate the timeline to a cure.

For years, scientific research has been conducted in relative isolation—one researcher or one institution working alone to tackle a major health issue. HHF developed the HRP Consortium model to do things differently. Our HRP scientists work on research projects together, share their unpublished data and tools, and collaborate on the development and refinement of the HRP’s strategic research plan. The group meets bi-annually in person, monthly by conference call, and communicates frequently by email. This continual dialogue is helping to eliminate repetitive work across the team, saving time and research dollars, and most importantly, accelerating the timetable to a cure.

Even though we are in the early stages of the research, we think it is very important that the public learn about our efforts. We want them to know that there is hope for a cure, and that there are researchers who consider curing hearing loss and tinnitus to be their life’s most important work. We hope our marketing efforts will help bring attention to the issue, raise awareness of the prospects for a cure and inspire other scientists and laypeople to join us in our support of this important research, so that we can find the cure as soon as possible.

But what about people with different forms of hearing loss: How can these research findings affect people born with hearing loss? People with late-in-life hearing loss?

There are two broad forms of hearing loss:

Conductive Hearing Loss is caused by any condition that blocks or impedes the conveyance of sound through the outer or middle ear. The result is a reduction in the sound intensity that reaches the cochlea. Common causes include ear infections, a perforation in the eardrum, or even buildup of earwax. Generally, conductive hearing loss can be treated with a complete or partial improvement in hearing.

Sensorineural Hearing Loss commonly occurs due to an injury or degenerative change in the inner ear and is currently permanent.

Damage to the hair cells in the inner ear is the most common type of sensorineural hearing loss. The Hearing Restoration Project is focused on the cure for sensorineural hearing loss, through the regeneration of these damaged inner ear hair cells, and with it the regeneration of hearing. Most types of age-related hearing loss and noise-induced hearing loss are caused by damage to these hair cells, making the HRP research applicable to most types of acquired hearing loss.

The amazing thing is that regeneration happens naturally and very robustly in almost all animals – mammals are the exception. This makes HHF and the researchers confident that we will find a way to stimulate this regeneration in mammals, including humans. While ten years may seem like a long time, and it is for someone like myself who lives with hearing loss every day, it is realistically within my lifetime, and that gives me hope and excites me for the future. While we wait for the cure, we encourage people with hearing loss to seek treatment for the condition through hearing aids or other means, so that they can enjoy the highest quality of life possible, while they wait.

What about tinnitus: How can these findings help the millions of people worldwide with ringing in their ears?

With 90% of tinnitus (ringing in the ears) occurring with an underlying hearing loss, a cure for hearing loss is also likely to be a cure for tinnitus. In a recent article in Hearing Health magazine, HHF’s free quarterly publication on all things related to hearing loss, this topic was discussed in detail. Some of the high points are detailed below:

There is certainly evidence that the restoration of hearing can alleviate tinnitus. For example, tinnitus can be induced by exposure to loud sounds that result in the temporary loss of hearing, which is experienced by many after attending a loud event like a rock concert. In most such cases, the tinnitus disappears as the hearing recovers.

Another example is the response of patients for whom otosclerosis (an abnormal bone growth in the middle ear) has induced a conductive hearing loss. Many such patients with this hereditary condition experience tinnitus. However, when their hearing is restored through a surgical procedure, many report an improvement in tinnitus.

Finally, there have been several reports that patients, after receiving a cochlear implant, experience a significant reduction in their tinnitus. Interestingly, in some cases this tinnitus suppression continues for several hours after the implant is turned off. Though the mechanism by which cochlear implants may suppress tinnitus is not clear, these observations all suggest that restoring function to the auditory system may be very helpful for tinnitus in a variety of ways.

There may be skepticism about ‘curing’ hearing loss. How would you respond to criticism toward curing hearing loss or deafness? For example, the Deaf community has a strong cultural identity shaped by living with deafness. Some would argue that a person’s deafness is what makes him/her unique, so why change it?

Hearing Health Foundation respects everyone’s individual choices and beliefs as relates to their hearing loss. For those interested in a biological cure, we are proud to be working on one.

This article was republished with permission.

HHF Included in Media Planet Vision and Hearing News

By Tara Guastella

For the second year, HHF is excited to be included in Media Planet’s Vision and Hearing News campaign. This annual initiative aims to raise awareness about vision and hearing loss, discuss new technologies, and provide expert commentary on the latest from the field. The campaign is included as an insert in USA Today and shared digitally, reaching millions of viewers worldwide.

This issue’s cover story features Seattle Seahawks fullback Derrick Coleman in an interview about his experience with hearing loss and the methods he took to succeed in his career. The interview is inspirational and it’s great to see Coleman as a role model for people with hearing loss.

Our exciting work to cure hearing loss and tinnitus is included within the issue in an article titled “The Promise for a Cure”. While technologies like hearing aids and cochlear implants bring great benefit to people with hearing loss, the article highlights how the work of our Hearing Restoration Project (HRP) aims to deliver a genuine, biologic cure for hearing loss and tinnitus within the next decade. By studying chickens, fish, and other animals who have the ability to naturally regenerate their inner ear hair cells and reverse hearing loss, our team of HRP researchers aims to translate the ability to restore hearing to people. Our PSA is also featured at the bottom of the article.

"Our organization has been at the forefront of hearing research for over half a century. Now we’re funding a genuine, biologic cure for hearing loss and tinnitus within the next decade. I can’t emphasize enough the importance of continued research in the hearing field,” says Shari Eberts, the chairman of HHF’s board of directors, in the article.

HHF Medical Director David Haynes, M.D., FACS, answers common questions about cochlear implants (CIs) and the types of hearing loss that may be eligible for CIs. “While standard hearing aids amplify sound, the cochlear implant has the capacity to break down sound and deliver this signal to specific areas of the cochlea, improving understanding,” Haynes says.

Lastly, we contributed an article about preventing hearing loss and the best ways to keep your, and your loved ones, hearing safe and sound. You can watch our interactive “How Hearing Works” video and also learn about walk, block, and turn. Our three-step method to prevent hearing damage advises walking away from loud sounds, blocking them with earplugs or earmuffs, and turning down the volume when it is under your control.

Check out the full Media Planet campaign for other hearing and vision resources.

Will Research on Chickens Provide a Solution to Needing Hearing Aids?

By Aaron Rodriques

Researchers hope to develop hearing loss treatments by studying the regenerative capabilities inner ear cells in chickens. We discovered some interesting info on these little guys and hearing aids. 

An Alternative to Hearing Aids

Scientists are on the path of a new application that could provide a unique alternative to hearing aids. By studying hair cells found in the inner ears of chickens, researchers are in the process of creating treatments that cure hearing loss in humans, minimizing the demand for hearing aids in the future.

Chickens can regenerate inner ear cells that replace cells damaged from noise and other forms of physical trauma. All vertebrates except mammals can exhibit this phenomenon. 

"The key to restoring hearing in humans is to regenerate cells deep within the inner ear," said Shari Eberts, chairwoman of the board of directors of the Hearing Health Foundation, which is funding the research. "While humans cannot regenerate hair cells in the inner ear after they are damaged, chickens can. In fact, most animals other than mammals can regenerate these delicate cells, restoring their hearing spontaneously after damage."

Hearing Aids and the Hearing Restoration Project

The Hearing Restoration Project (HRP) involves researchers from more than 10 institutions including Harvard Medical School, who are studying chickens in order to find out how humans could possibly regenerate inner ear cells. 

Approximately 36 million adults in the U.S. have some kind of hearing loss, and 25 million have tinnitus, according to the National Institute of Deafness and Other Communication Disorders. The Hearing Health Foundation aims to manufacture a cure by 2024.

According to Eberts, researchers are studying fish and mice as well. Fish can regenerate hair cells like chickens, but mice cannot.

"By analyzing what genes allow for regeneration in fish and chickens, we can compare those to mouse genes to see where the differences occur," she said. "Once we have an understanding of what genes and sets of genes (known as pathways) play a role in allowing for regeneration in fish and chickens, and which inhibit regeneration in mice, we will have a clearer understanding of how to trigger regeneration in humans."

Animal Biology and Hearing Aid Design

Similar studies with different animal species have found them to have unique hearing capabilities that offer promising new innovations for hearing aid technology. This includes the impressive hearing abilities of the Greater Wax Moth, a tiny insect found in beehives, and the unique anatomy of the locust. Hearing aids based on structures found in nature are considered to have a “biomimetic design.”

This article was republished with permission from Audicus.

Can Plants Hear?

By Yishane Lee

As a friend of HHF, you are no doubt well aware that chicks, fish, and reptiles have the ability to regenerate their inner ear hair cells, an ability that means any damage to their hearing is corrected.

Mammals, including humans, cannot, and this is the core of what HHF’s Hearing Restoration Project is working to solve within the next decade—how we can translate the chick’s ability to regrow hair cells to humans, and as a result find a biologic cure for hearing loss and tinnitus.

Now comes news that it is not just the animal world that can hear. Plants can, too. A recent story by Michael Pollan in the New Yorker included this paragraph (italics mine):

“Plants have evolved between 15 and 20 distinct senses, including analogues of our five: smell and taste (they sense and respond to chemicals in the air or on their bodies); sight (they react differently to various wavelengths of light as well as to shadow); touch (a vine or a root ‘knows’ when it encounters a solid object); and, it has been discovered, sound. In a recent experiment, Heidi Appel, a chemical ecologist at the University of Missouri, found that, when she played a recording of a caterpillar chomping a leaf for a plant that hadn’t been touched, the sound primed the plant’s genetic machinery to produce defense chemicals. Another experiment, done in [Italian plant physiologist Stefano] Mancuso’s lab and not yet published, found that plant roots would seek out a buried pipe through which water was flowing even if the exterior of the pipe was dry, which suggested that plants somehow ‘hear’ the sound of flowing water.”

I find this absolutely fascinating. Could it be the plants “hear” via sensing sound vibrations—just like we do? And then they’re able to correctly correlate these vibrations to the category of friend or foe—again, just like we do? To hear the plant biologists in the story put it: Yes, it’s entirely possible, and even likely.

The article raises interesting issues of why animal-based biology deserves primacy, and whether a typical (animal) brain is needed for something to be considered intelligent. In addition to reading the piece, which I highly encourage you to do, there is a TED Talk by Mancuso, if you want to learn more.

We can learn much from plants. The promise of the Hearing Restoration Project is that we can also learn much from chicks, fish, and reptiles. Indeed, there has been early success with hair cell regeneration in mice.

Support the search for a cure for hearing loss and tinnitus within a decade.

How Can a Chicken Cure Hearing Loss & Tinnitus? Find out in our new PSA!

By Tara Guastella

I’m so excited to share that we have recently launched a new Public Service Announcement (PSA): Chirp the News! The PSA introduces HHF’s new mascot, a baby chicken.

Why a baby chicken?

The key to restoring hearing in humans is to regenerate cells deep within the inner ear. In fact, most types of hearing loss in humans results from damage to these cells, called hair cells. While humans cannot regenerate hair cells in the inner ear after they are damaged, chickens can. In fact, most animals other than mammals can regenerate these delicate cells, restoring their hearing spontaneously after damage.

This knowledge is the basis for our Hearing Restoration Project (HRP). The HRP is a consortium of over a dozen top scientists from across the world working collaboratively to take what we know happens in chickens and translate that to people. Our HRP scientists estimate clinical trials testing a genuine, biologic cure for hearing loss can occur within the next decade. Since over 90 percent of tinnitus cases occur with an underlying hearing loss, a cure for hearing loss is also likely the key to a cure for tinnitus.

Most scientific research is conducted in isolation: one researcher or one lab trying to solve a major health issue. Our unique HRP consortium model is breaking the mold by encouraging our scientists to work as a team sharing data, tools, resources, and ideas. By working collaboratively, the timeline to a cure is expedited: five times as fast with the power of collaboration.

We won’t be able to get to a cure for hearing loss and tinnitus without your help—please donate today and be a part of the cure.

Innovative Science Meets Innovative Technology

By Yishane Lee

This month our own Tara Guastella was interviewed for a piece on the blog for Exponent Partners. Exponent Partners is HHF’s technology partner who implemented our new online grants management system called Foundation Connect in mid- to late 2012. Foundation Connect has greatly increased HHF’s efficiency, transparency, and accountability, allowing us to match our innovative hearing research with innovative grants management.

In the interview, Tara speaks about HHF’s mission and research efforts, highlighting why hearing research affects everyone and how the new system has benefitted HHF:

HHF’s mission is to prevent and cure hearing loss and tinnitus through groundbreaking research. Our HRP researchers are specifically studying regrowth of the tiny sensory cells inside everyone’s ears, called hair cells, which allow us to hear. Every time we damage them with exposure to loud noise, or the cells are otherwise destroyed—such as by certain drugs or simply aging—we are at risk for hearing loss.

Normally, in humans, these cells do not grow back. However, researchers funded by HHF have found promising leads in the hair cells of chickens, which naturally regrow. The research suggests that regeneration of these cells could be induced in mammals. This would combat one of the most widespread forms of acquired hearing loss. It is estimated that 10 percent of Americans between the ages of 20 and 69 may have suffered hearing loss from noise exposure.

This type of loss is also highly associated with tinnitus, or ringing in the ears, found in 90 percent of tinnitus cases. Researchers are hopeful that once hearing is restored, tinnitus will similarly be alleviated. This would bring great benefit to the nearly 50 million Americans who experience hearing loss or tinnitus, including one in five teens and 60 percent of recently returning veterans.

HHF funds not only this research toward a cure but also many other hearing topic areas, including auditory processing disorders, genetic hearing loss, and the vestibular (balance) system, to name a few.

“Fifty years ago, restoring hearing to a person with hearing loss seemed like a dream,” Guastella said. “Since then, HHF has contributed to many of today’s current treatment options such as cochlear implants, new therapies for ear infections, and therapy for otosclerosis [an abnormal bone growth in the ear].”

Guastella noted, “When we first launched the HRP, one of our goals was to make the application and review process as easy and efficient as we could. We wanted our consortium scientists to dedicate as much time as possible to advancing the research in their labs rather than spending time applying for grants.”

The system has increased the capacity of the foundation. “We were able to process double the amount of letters of inquiry the year after we implemented the solution. We can quickly respond to inquiries about our past grantees as well,” Guastella said. “And everything is more user-friendly.” Now HHF’s internal grants administration matches the cutting-edge research they support.

Read the rest of the Exponent Partners blog post here.

Support a Cure for Hearing Loss and Get Your Tax Deduction Before 2013 Ends!

By Tara Guastella

What’s a better way to take part in the season of giving than by making a tax deductible donation and showing your support for a cure for hearing loss and tinnitus? I can’t think of any!

This time of year, charities always see an influx in gifts with many donors waiting until the last minute to write their check or go online to donate. Last year, we broke records in the amount of charitable gifts that came in during the fourth quarter and this year we hope to do so yet again!  Will you help us break records by making a year end, tax deductible gift?

Why should you donate to HHF this year? Kille, a mother of three sons (two have hearing loss), recently shared: "When I stumbled upon HHF's free magazine, Hearing Health, I said to myself 'Thank goodness there is an organization out there working on offering a cure for hearing loss for those who want it. And I want to be part of making that a reality.'"

We hope you will join Kille. There are many ways you can support HHF and a cure for hearing loss and tinnitus this giving season:

• Make an online donation (before December 31).

• Mail in a donation (remember it must be postmarked and the check date must be no later than Dec. 31); see our mailing address in the footer below.

• Contribute to an item on our Wish List and give our researchers the tools they need to conduct their studies.

• Create a giving page or fundraising event where you can raise funds from family and friends.

• Make a donation in honor of or in memory of someone special to you.

• Give a gift of appreciated stock from an IRA or a gift of life insurance.

Which way will you show your support? Share in the comments!

Give the Gift of Healthy Hearing

By Yishane Lee

As soon as the holidays roll around every year, I try to think of ways to give and receive gifts that are truly valuable, and not merely the season’s hot toy or other things that, when it comes down to it, you don’t really, really need. (I have used last year’s immersion blender exactly once. Yipes!)

As I try to remind my kids, the season is about gift giving, not receiving, and this year, I’ll talk to my family about giving the gift of healthy hearing. An annual hearing test taken every year around the holidays is the perfect way to show your family you care, and for them to show you they care.

Why? Undiagnosed and untreated hearing loss has been shown to detrimentally affect personal relationships, as the Better Hearing Institute reports. “Research demonstrates the considerable negative social, psychological, cognitive, and health effects of untreated hearing loss with far-reaching implications that go well beyond hearing alone. In fact, those who have difficulty hearing can experience such distorted and incomplete communication that it seriously impacts their professional and personal lives, at times leading to isolation and withdrawal.”

And it’s well known that social isolation is a risk factor for dementia and other cognitive disorders. The social isolation that can come with untreated hearing loss may be one reason why hearing loss has been linked to dementia, according to a 2011 study led by Frank Lin, M.D., Ph.D., at the Johns Hopkins School of Medicine. It is also possible that whatever leads to dementia may also cause hearing loss. Or, the brain’s constant efforts to understand and interpret sounds eventually taxes the brain, leading to dementia.

I don’t mean to be such a downer in a time of holiday cheer. But since having a hearing loss can be even more challenging during the holidays, when family and friends gather and when the noise level can be even louder, you owe it to yourself and your family—and vice versa—to get your hearing checked by a hearing professional this holiday season.

If you’re really looking to give a gift that will impact a cure for hearing loss and tinnitus, consider a gift to HHF.  You can make a gift in memory or in honor of a loved one, contribute to an item on our wish list, or fundraise for a cure and ask your family and friends to donate to HHF in lieu of holiday gifts to you.

While you are doing some online shopping, consider using Amazon Smile where a portion of your proceeds will be automatically donated to HHF at no cost to you! Just register (or sign in to your Amazon account) and choose HHF as your charity of choice. Also, be sure to avoid these toxic toys—including noisy toys that have the potential to cause hearing damage over time.

Here’s hoping you and yours enjoy a happy, healthy holiday season!

You Can Help Us Find a Cure!

By Tara Guastella

Do you, or a family member, or a friend have a hearing loss? Do you know someone returning from military service who developed a hearing loss or tinnitus while serving our country? Do you want to help us find a cure for hearing loss and tinnitus?

Help us fundraise for a cure!  

We are excited to announce the launch of our new giving platform that will help you do just that. Join us in finding a cure for hearing loss and tinnitus by creating a fundraising event for Giving Tuesday, on December 3 this year, an international day of giving that kicks off the holiday giving season.

But don’t worry--if you aren’t able to plan something for for Giving Tuesday, no problem. Our giving platform will be available to you year-round for any event or giving idea that you may have.

There are many different ways to create your own fundraising event, ranging from golf outings and bake sales, to birthdays and weddings, to marathons and triathlons. Let your talents and interests lead you--no event is too large or too small!

If you’re looking for a unique way to create a fundraising event, we have several examples of past events, such as Publishing for Vision & Hearing and DJ’ing for a Cure, alongside more traditional sporting event examples like the NYC Marathon, Marine Corp Marathon, and Aquaphor NYC Triathlon. Looking for other ideas? We have those for you too!

If you’ve never fundraised before, don’t let that stop you. We provide email templates and examples of how to reach out to friends and family to ask for support of your event. We also provide a host of social media sharing options. Did you know the average person has 300 friends on Facebook? If you create an event and ask each of your Facebook friends to donate $5, you can raise $1,500!

Once you’ve nailed down how you’d like to fundraise, in three easy steps you’ll be on your way to helping us support groundbreaking research to cure hearing loss and tinnitus. 1.) Register; 2) Create your Giving Page; 3) Share your personal page with family and friends and ask for their support.

Get Started!

Thank you in advance for your help toward finding a cure for hearing loss and tinnitus.

Have questions or need help setting up your fundraiser?  Email fundraise@hhf.org or call (212) 257-6140.