The challenge is hearing in noisy environments. In humans, evidence suggests that difficulty hearing in noisy, social settings may reflect premature auditory nerve degeneration. We report finding deterioration in perception in noisy environments after inducing bilateral moderate auditory nerve degeneration in adult mice.
Register for Hearing Health Hour Webinar: Measuring Tinnitus and Reactions to Tinnitus
Join us for the next installment in our complimentary webinar series, Hearing Health Hour, on Monday, April 19, 2021 at 5:00 PM EST. The webinar is entitled “Measuring Tinnitus and Reactions to Tinnitus,” and will be led by past Emerging Research Grants (ERG) scientist Richard Tyler, Ph.D.
Evaluation of a New Method for Measuring Pediatric Hearing
In our method, a child is trained to perform a play-based task when a signal is heard. An experimenter—called an observer—watches the child’s behavior to determine when the signal was played. In contrast to clinical testing methods, the signal is randomly placed in one of two intervals for each trial by the computer program.
Meet the 2020 ERG Researchers
These seven early career scientists were chosen through a rigorous review by HHF’s Scientific Review Committee and Council of Scientific Trustees, comprising senior expert scientists and physicians from across the U.S. The researchers are investigating a range of hearing and balance areas and also, as demonstrated in our Meet the Researcher column, have diverse interests in their free time, which more often than not informs their work.
Chloroquine to Fight COVID-19: Mechanisms and Adverse Effects
The COVID-19 outbreak emerged in December 2019 and has rapidly become a global pandemic. A great deal of effort has been made to find effective drugs against this disease. Two structurally related quinoline drugs, chloroquine (CQ) and hydroxychloroquine (HCQ), were widely adopted in treating COVID-19, but the results were contradictory.
Age-Related Hearing Loss and Brainwave Changes
Brain oscillations (brainwaves) are associated with specific cognitive and sensory processes. How age-related hearing loss (presbycusis) alters the oscillations is unclear. Age-related speech recognition problems can be caused by changes in neurotransmission (chemical messaging between nerve cells) and temporal processing (the perception of sound within a defined time frame).
Emerging Research Grants (ERG) Applications Are Open
Through the Emerging Research Grants (ERG) program, Hearing Health Foundation (HHF) provides seed money to researchers working across the entire spectrum of hearing research and balance research, including many underfunded areas of otology. The ERG program has since 1958 played a foundational role in the careers of many academic researchers and clinicians in otolaryngology and related hearing and balance fields.
Effects of Premature Birth on the Auditory System
In our August 2020 paper in The Hearing Journal, we review causes of prematurity and the typical development of the auditory system. The sensory system, which includes the auditory system, develops in a very specific way inside the womb. This process is interrupted and occurs differently when development continues outside of the womb due to a premature birth.
Investigating the Interaction of Auditory and Pain Pathways
As the intensity of a sound increases, typical-hearing listeners experience an increase in loudness, but for levels above 120 decibels (dB), listeners not only perceive the sound as extremely loud, but also painful—the aural threshold of pain. Some individuals with hearing loss and other neurological disorders perceive even moderate-intensity sounds as both painful and loud, a condition known as pain hyperacusis.
2020-2021 Scientific Grantees Announced
Scientific researchers have, like all of us, faced numerous challenges over the past months of the COVID-19 crisis, but have continued the science throughout, whether in reduced occupancy labs or remote, driven by their dedication to advance knowledge and contribute to the treatment and, ultimately, cure for hearing loss and other hearing and balance disorders. HHF’s donors have shown similar dedication, and HHF is happy to provide research funding to the exceptionally promising projects below.